Elmore Susan A, Hoenerhoff Mark, Katsuta Osamu, Kokoshima Hiroko, Maronpot Robert, Nagai Hiroaki, Satoh Hiroshi, Tanaka Yasuhiro, Tochitani Tomoaki, Tsuchiya Seiichiro, Yoshizawa Katsuhiko
National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, 111 T.W. Alexander Drive, Research Triangle Park, North Carolina 27709, USA.
J Toxicol Pathol. 2013 Jun;26(2):231-57. doi: 10.1293/tox.26.231. Epub 2013 Jul 10.
The first joint Japanese Society of Toxicologic Pathology (JSTP) and National Toxicology Program (NTP) Satellite Symposium, entitled "Pathology Potpourri," was held on January 29(th) at Okura Frontier Hotel in Tsukuba, Ibaraki, Japan, in advance of the JSTP's 29(th) Annual Meeting. The goal of this Symposium was to present current diagnostic pathology or nomenclature issues to the toxicologic pathology community. This article presents summaries of the speakers' presentations, including diagnostic or nomenclature issues that were presented, select images that were used for audience voting or discussion, and the voting results. Some lesions and topics covered during the symposium include: treatment-related atypical hepatocellular foci of cellular alteration in B6C3F1 mice; purulent ventriculoencephalitis in a young BALB/c mouse; a subcutaneous malignant schwannoma in a RccHan:WIST rat; spontaneous nasal septum hyalinosis/eosinophilic substance in B6C3F1 mice; a rare pancreatic ductal cell adenoma in a young Lewis rat; eosinophilic crystalline pneumonia in a transgenic mouse model; hyaline glomerulopathy in two female ddY mice; treatment-related intrahepatic erythrocytes in B6C3F1 mice; treatment-related subendothelial hepatocytes in B6C3F1 mice; spontaneous thyroid follicular cell vacuolar degeneration in a cynomolgus monkey; congenital hepatic fibrosis in a 1-year-old cat; a spontaneous adenocarcinoma of the middle ear in a young Crl:CD(SD) rat; and finally a series of cases illustrating some differences between cholangiofibrosis and cholangiocarcinoma in Sprague Dawley and F344 rats.
日本毒理病理学会（JSTP）和美国国家毒理学计划（NTP）联合举办的首届卫星研讨会，主题为“病理杂烩”，于1月29日在日本茨城县筑波市的大仓前沿酒店举行，先于JSTP第29届年会。本次研讨会的目的是向毒理病理学领域介绍当前的诊断病理学或命名问题。本文介绍了演讲者的演讲摘要，包括所提出的诊断或命名问题、用于观众投票或讨论的精选图像以及投票结果。研讨会上涉及的一些病变和主题包括：B6C3F1小鼠中与治疗相关的细胞改变的非典型肝细胞灶；一只年轻BALB/c小鼠的化脓性脑室脑炎；一只RccHan:WIST大鼠的皮下恶性神经鞘瘤；B6C3F1小鼠自发性鼻中隔透明变性/嗜酸性物质；一只年轻Lewis大鼠罕见的胰腺导管细胞腺瘤；转基因小鼠模型中的嗜酸性结晶性肺炎；两只雌性ddY小鼠的玻璃样肾小球病；B6C3F1小鼠中与治疗相关的肝内红细胞；B6C3F1小鼠中与治疗相关的内皮下肝细胞；食蟹猴自发性甲状腺滤泡细胞空泡变性；一只1岁猫的先天性肝纤维化；一只年轻Crl:CD(SD)大鼠中耳自发性腺癌；最后是一系列病例，说明了Sprague Dawley和F344大鼠胆管纤维化和胆管癌之间的一些差异。
