Boorman Gary, Crabbs Torrie A, Kolenda-Roberts Holly, Latimer Ken, Miller Andrew D, Muravnick Kathleen B, Nyska Abraham, Ochoa Ricardo, Pardo Ingrid D, Ramot Yuval, Rao Deepa B, Schuh JoAnn, Suttie Andrew, Travlos Greg S, Ward Jerrold M, Wolf Jeffrey C, Elmore Susan A
Covance Laboratories, Inc., Chantilly, Virginia, USA.
Toxicol Pathol. 2012;40(2):321-44. doi: 10.1177/0192623311427713. Epub 2011 Nov 16.
The 2011 annual National Toxicology Program (NTP) Satellite Symposium, entitled "Pathology Potpourri," was held in Denver, Colorado in advance of the Society of Toxicologic Pathology's 30th Annual Meeting. The goal of the NTP Symposium is to present current diagnostic pathology or nomenclature issues to the toxicologic pathology community. This article presents summaries of the speakers' presentations, including diagnostic or nomenclature issues that were presented, along with select images that were used for audience voting or discussion. Some lesions and topics covered during the symposium include: proliferative lesions from various fish species including ameloblastoma, gas gland hyperplasia, nodular regenerative hepatocellular hyperplasia, and malignant granulosa cell tumor; spontaneous cystic hyperplasia in the stomach of CD1 mice and histiocytic aggregates in the duodenal villous tips of treated mice; an olfactory neuroblastoma in a cynomolgus monkey; various rodent skin lesions, including follicular parakeratotic hyperkeratosis, adnexal degeneration, and epithelial intracytoplasmic accumulations; oligodendroglioma and microgliomas in rats; a diagnostically challenging microcytic, hypochromic, responsive anemia in rats; a review of microcytes and microcytosis; nasal lesions associated with green tea extract and Ginkgo biloba in rats; corneal dystrophy in Dutch belted rabbits; valvulopathy in rats; and lymphoproliferative disease in a cynomolgus monkey.
2011年国家毒理学计划(NTP)年度卫星研讨会,题为“病理学杂烩”,在科罗拉多州丹佛市毒理病理学会第30届年会之前举行。NTP研讨会的目标是向毒理病理学领域介绍当前的诊断病理学或命名问题。本文介绍了演讲者的发言摘要,包括所提出的诊断或命名问题,以及用于观众投票或讨论的精选图片。研讨会期间涵盖的一些病变和主题包括:来自各种鱼类的增殖性病变,包括成釉细胞瘤、气腺增生、结节性再生性肝细胞增生和恶性颗粒细胞瘤;CD1小鼠胃中的自发性囊性增生和经处理小鼠十二指肠绒毛尖端的组织细胞聚集;一只食蟹猴的嗅神经母细胞瘤;各种啮齿动物皮肤病变,包括滤泡性角化不全性角化过度、附属器变性和上皮细胞内蓄积;大鼠的少突胶质细胞瘤和小胶质细胞瘤;大鼠一种诊断上具有挑战性的小细胞低色素性反应性贫血;对小红细胞和小红细胞症的综述;大鼠中与绿茶提取物和银杏相关的鼻部病变;荷兰带兔的角膜营养不良;大鼠的瓣膜病;以及一只食蟹猴的淋巴增殖性疾病。