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2014年国家毒理学计划卫星研讨会会议记录

Proceedings of the 2014 National Toxicology Program Satellite Symposium.

作者信息

Elmore Susan A, Cora Michelle C, Gruebbel Margarita M, Hayes Schantel A, Hoane Jessica S, Koizumi Haruko, Peters Rachel, Rosol Thomas J, Singh Bhanu P, Szabo Kathleen A

机构信息

National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA

National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA.

出版信息

Toxicol Pathol. 2015 Jan;43(1):10-40. doi: 10.1177/0192623314555526. Epub 2014 Nov 9.

Abstract

The 2014 annual National Toxicology Program (NTP) Satellite Symposium, entitled "Pathology Potpourri" was held in Washington, D.C., in advance of the Society of Toxicologic Pathology's 33rd annual meeting. The goal of this annual NTP Symposium is to present current diagnostic pathology or nomenclature issues to the toxicologic pathology community. This article presents summaries of the speakers' presentations, including diagnostic or nomenclature issues that were presented, along with select images that were used for audience voting and discussion. Some lesions and topics covered during the symposium included a pulmonary mucinous adenocarcinoma in a male B6C3F1 mouse; plexiform vasculopathy in Wistar Han (Crl:WI[Han]) rats; staging of the estrous cycle in rats and mice; peri-islet fibrosis, hemorrhage, lobular atrophy and inflammation in male Sprague-Dawley (SD) rats; retinal dysplasia in Crl:WI[Han] rats and B6C3F1 mice; multicentric lymphoma with intravascular microemboli and tumor lysis syndrome, and 2 cases of myopathy and vascular anomaly in Tg.rasH2 mice; benign thymomas in Crl:WI[Han] rats; angiomatous lesions in the mesenteric lymph nodes of Crl:WI[Han] rats; an unusual foveal lesion in a cynomolgous monkey; and finally a series of nomenclatures challenges from the endocrine International Harmonization of Nomenclature and Diagnostic Criteria (INHAND) Organ Working Group (OWG).

摘要

2014年国家毒理学项目(NTP)年度卫星研讨会,题为“病理学杂烩”,于毒理病理学会第33届年会之前在华盛顿特区举行。本次NTP年度研讨会的目标是向毒理病理学领域介绍当前的诊断病理学或命名问题。本文介绍了演讲者的发言摘要,包括所提出的诊断或命名问题,以及用于观众投票和讨论的精选图片。研讨会期间涵盖的一些病变和主题包括雄性B6C3F1小鼠的肺黏液腺癌;Wistar Han(Crl:WI[Han])大鼠的丛状血管病;大鼠和小鼠发情周期的分期;雄性Sprague-Dawley(SD)大鼠的胰岛周围纤维化、出血、小叶萎缩和炎症;Crl:WI[Han]大鼠和B6C3F1小鼠的视网膜发育异常;伴有血管内微栓子和肿瘤溶解综合征的多中心淋巴瘤,以及Tg.rasH2小鼠的2例肌病和血管异常病例;Crl:WI[Han]大鼠的良性胸腺瘤;Crl:WI[Han]大鼠肠系膜淋巴结的血管瘤样病变;食蟹猴的一种不寻常的中央凹病变;最后是内分泌国际命名和诊断标准协调(INHAND)器官工作组(OWG)提出的一系列命名挑战。

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