Engdahl Johan, Holmén Anders, Rosenqvist Mårten, Strömberg Ulf
Department of Medicine, Halland Hospital, SE-301 85 Halmstad, Sweden.
BMC Public Health. 2013 Aug 3;13:715. doi: 10.1186/1471-2458-13-715.
In a screening study for silent atrial fibrillation (AF), which is a frequent source of cardiac emboli with ischemic stroke, the proportion of non-participants was considerable and their clinical profile differed from the participants' profile. We intended to geo-map the target population and non-participation in an attempt to understand factors related to screening uptake and, thereby, obtain useful information needed to intervene for improved uptake.
In the municipality of Halmstad, Sweden, all residents born in 1934-1935 were invited to the screening study during April 2010 to February 2012. The total study group included 848 participants and 367 non-participants from 12 parishes. Geo-maps displaying participation, along with target-population-based geo-maps displaying proportion of immigrants and ischemic stroke incidence, were used.
Smoothed non-participation ratios (SmNPR) varied from 0.81 to 1.24 across different parishes (SmNRP=1 corresponds to the expected participation based on the total study group). Among high risk individuals, the geographical variation was more pronounced (SmNPR range 0.75-1.51). Two parishes with higher share of immigrants and elevated population-based ischemic stroke incidence showed markedly lower participation, particularly among high-risk individuals.
AF screening uptake varied evidently between parishes, particularly among high-risk individuals. Geo-mapping of target population and non-participation yielded useful information needed to intervene for improved screening uptake.
在一项针对无症状性心房颤动(AF)的筛查研究中,无症状性心房颤动是心脏栓子导致缺血性卒中的常见原因,未参与者的比例相当可观,且他们的临床特征与参与者不同。我们试图对目标人群和未参与情况进行地理映射,以了解与筛查接受度相关的因素,从而获取改善接受度所需的有用干预信息。
在瑞典哈尔姆斯塔德市,所有1934年至1935年出生的居民在2010年4月至2012年2月期间被邀请参加筛查研究。整个研究组包括来自12个教区的848名参与者和367名未参与者。使用了展示参与情况的地理地图,以及基于目标人群展示移民比例和缺血性卒中发病率的地理地图。
不同教区的平滑未参与率(SmNPR)在0.81至1.24之间变化(SmNRP = 1对应基于整个研究组的预期参与率)。在高危个体中,地理差异更为明显(SmNPR范围为0.75 - 1.51)。两个移民比例较高且基于人群的缺血性卒中发病率较高的教区参与率明显较低,尤其是在高危个体中。
AF筛查接受度在不同教区之间明显不同,尤其是在高危个体中。对目标人群和未参与情况进行地理映射产生了改善筛查接受度所需的有用干预信息。