Nicolson L, Cullinane A A, Onions D E
Department of Veterinary Pathology, University of Glasgow Veterinary School, Bearsden, U.K.
J Gen Virol. 1990 Aug;71 ( Pt 8):1801-5. doi: 10.1099/0022-1317-71-8-1801.
We have determined the genomic location and nucleotide sequence of the equine herpesvirus 4 thymidine kinase (TK) gene. The gene is positioned at approximately 0.48 map units within the long unique component of the genome and is flanked by genes encoding a herpes simplex virus 1 (HSV-1) UL24 homologue and glycoprotein H. The predicted protein is composed of 352 amino acids, has an Mr of 38,800 and exhibits 36% identity to the predicted TK of HSV-1.
我们已经确定了马疱疹病毒4胸苷激酶（TK）基因的基因组定位和核苷酸序列。该基因位于基因组长独特组分内约0.48个图距单位处，两侧分别是编码单纯疱疹病毒1型（HSV-1）UL24同源物和糖蛋白H的基因。预测的蛋白质由352个氨基酸组成，分子量为38,800，与HSV-1预测的TK具有36%的同一性。
