Griffin A M, Boursnell M E
AFRC Institute for Animal Health, Houghton Laboratory, Huntingdon, Cambridgeshire, U.K.
J Gen Virol. 1990 Apr;71 ( Pt 4):841-50. doi: 10.1099/0022-1317-71-4-841.
We have sequenced a 5.4 kb region of the genome from the avian herpesvirus infectious laryngotracheitis virus (ILTV) and identified genes homologous to the thymidine kinase (TK) gene, the capsid p40 gene of herpes simplex virus type 1 (HSV-1), a gene encoding a protein antigenic in Epstein-Barr virus infections plus one other highly conserved gene encoding a protein implicated in cell fusion in HSV-1. Computer analysis of the TK gene and the upstream overlapping gene sequence is used to produce trees showing potential evolutionary relationships between the herpesvirus subfamilies.
我们对禽疱疹病毒传染性喉气管炎病毒（ILTV）基因组的一个5.4 kb区域进行了测序，并鉴定出与胸苷激酶（TK）基因、单纯疱疹病毒1型（HSV-1）的衣壳p40基因、一种在爱泼斯坦-巴尔病毒感染中具有抗原性的蛋白质编码基因以及另一个与HSV-1细胞融合相关的高度保守蛋白质编码基因同源的基因。对TK基因和上游重叠基因序列进行计算机分析，以绘制显示疱疹病毒亚科之间潜在进化关系的树形图。
