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具有同时宫颈内型和肠型黏液分化的子宫内膜样腺癌：一种罕见现象及免疫组化表型的报道。

Endometrioid adenocarcinoma with simultaneous endocervical and intestinal-type mucinous differentiation: report of a rare phenomenon and the immunohistochemical profile.

机构信息

Department of Pathology and Laboratory Medicine, Women & Infants Hospital and the Warren Alpert Medical School of Brown University, 101 Dudley Street, Providence, RI 02905, USA.

出版信息

Diagn Pathol. 2013 Aug 2;8:128. doi: 10.1186/1746-1596-8-128.

DOI:10.1186/1746-1596-8-128
PMID:23915109
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3849525/
Abstract

UNLABELLED

Intestinal differentiation in the endometrium is rare with only case reports in the international literature. We describe a case of simultaneous endocervical and intestinal-type mucinous differentiation with goblet cells arising in a FIGO grade 1 endometrioid adenocarcinoma. The patient had no involvement of the myometrium, cervix, or extra-uterine sites. There were no intestinal metaplastic changes of the endocervical canal. The etiology of this change is unknown, although recent reports suggest an association with hyperestrogenism.

VIRTUAL SLIDES

The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1209512176931698.

摘要

未注明

国际文献中仅有个案报道称子宫内膜中有肠分化，非常罕见。我们描述了 1 例国际妇产科联盟（FIGO）分级 1 型子宫内膜样腺癌中同时出现宫颈内口和肠型黏液分化，并伴有杯状细胞的病例。患者的子宫肌层、宫颈或其他子宫外部位均无累及。宫颈管内也没有肠上皮化生改变。尽管最近有报道称这种变化与雌激素过高有关，但这种变化的病因尚不清楚。

虚拟幻灯片

本文的虚拟幻灯片可在此处找到：http://www.diagnosticpathology.diagnomx.eu/vs/1209512176931698。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28db/3849525/926721ff9bfd/1746-1596-8-128-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28db/3849525/926721ff9bfd/1746-1596-8-128-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28db/3849525/926721ff9bfd/1746-1596-8-128-1.jpg

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Gynecol Oncol Rep. 2022 Oct 7;44:101078. doi: 10.1016/j.gore.2022.101078. eCollection 2022 Dec.
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