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细菌性阴道病相关厌氧菌初始黏附到 ME-180 细胞的定量分析。

Quantitative analysis of initial adhesion of bacterial vaginosis-associated anaerobes to ME-180 cells.

机构信息

IBB - Institute for Biotechnology and Bioengineering, Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal; Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond, VA 23298-0678, USA.

出版信息

Anaerobe. 2013 Oct;23:1-4. doi: 10.1016/j.anaerobe.2013.07.007. Epub 2013 Aug 2.

Abstract

Bacterial vaginosis is the leading vaginal disorder but the transition from health to this dysbiotic condition remains poorly characterized. Our goal was to quantify the ability of BV-associated anaerobes to adhere to epithelial cells in the presence of lactobacilli. Gardnerella vaginalis outcompeted Lactobacillus crispatus and Lactobacillus iners actually enhanced its adherence.

摘要

细菌性阴道病是最常见的阴道疾病,但从健康到这种生态失调状态的转变仍未得到充分描述。我们的目标是定量评估 BV 相关厌氧菌在乳酸杆菌存在的情况下黏附上皮细胞的能力。阴道加德纳菌(Gardnerella vaginalis)与卷曲乳杆菌(Lactobacillus crispatus)和惰性乳杆菌(Lactobacillus iners)竞争,实际上增强了其黏附能力。

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