Don C. Gnocchi Foundation, ONLUS, Milano, Italy.
J Hosp Infect. 2013 Sep;85(1):66-8. doi: 10.1016/j.jhin.2013.06.007. Epub 2013 Aug 2.
Kaposi sarcoma (KS)-associated herpesvirus (KSHV or HHV-8) infection routes and risk of occupational exposure are still ill-defined. We analysed the risk for occupational acquisition of KSHV infection in healthcare workers (HCWs) with prolonged professional exposure to patients with classic KS, comparing the results to those obtained in healthy relatives of KS patients. Serum and/or saliva KSHV-specific antibodies and DNA were detected in five out of 35 healthy relatives of KS patients but in none of the eight HCWs, suggesting that, outside strict family contacts, horizontal transmission of KSHV is highly inefficient even for HCWs with prolonged contact with KS patients.
卡波西肉瘤（KS）相关疱疹病毒（KSHV 或 HHV-8）的感染途径和职业暴露风险仍不明确。我们分析了长期接触经典 KS 患者的医护人员（HCWs）职业性获得 KSHV 感染的风险，将结果与 KS 患者健康亲属的结果进行比较。在 35 名 KS 患者的健康亲属中有 5 人血清和/或唾液中检测到 KSHV 特异性抗体和 DNA，但在 8 名 HCWs 中均未检测到，这表明，即使是与 KS 患者有长期接触的 HCWs，除了严格的家庭接触外，KSHV 的水平传播效率也非常低。
