Bettini S, Gramiccia M, Gradoni L, Biggio P, Loi R, Cottoni F, Pau M, Atzeni M C
Istituto di Zoologia, Università di Cagliari, Italy.
J Trop Med Hyg. 1990 Aug;93(4):262-9.
Cutaneous leishmaniasis (CL) is endemic in Sardinia where 250 cases were reported from 1922 to 1988. The province of Sassari, in the north of the island, shows the highest number of cases. The vertical distribution of localities where cases had occurred is analysed and the age distribution of cases is given. Isolation of parasites was attempted in 12 cases, but successful growth of Leishmania was obtained from three cultures only. The stocks belonged to two different zymodemes of L. infantum: zymodeme Montpellier (ZMON) 24 and ZMON 24 MPI variant. The distribution of dermotropic L. infantum zymodemes in the Mediterranean area is discussed and the presence of a possible parasite reservoir is suggested.
皮肤利什曼病（CL）在撒丁岛呈地方性流行，1922年至1988年期间报告了250例病例。该岛北部的萨萨里省病例数最多。分析了病例发生地点的垂直分布情况，并给出了病例的年龄分布。对12例病例尝试进行寄生虫分离，但仅从三种培养物中成功培养出利什曼原虫。这些菌株属于婴儿利什曼原虫的两个不同酶谱型：蒙彼利埃酶谱型（ZMON）24和ZMON 24 MPI变体。讨论了嗜皮性婴儿利什曼原虫酶谱型在地中海地区的分布情况，并提出了可能存在寄生虫储存宿主的观点。
