感觉神经节中神经元胞体与卫星胶质细胞之间的通讯。
Communication between neuronal somata and satellite glial cells in sensory ganglia.
机构信息
Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas 77555-1069, USA.
出版信息
Glia. 2013 Oct;61(10):1571-81. doi: 10.1002/glia.22541. Epub 2013 Aug 5.
Abstract
Studies of the structural organization and functions of the cell body of a neuron (soma) and its surrounding satellite glial cells (SGCs) in sensory ganglia have led to the realization that SGCs actively participate in the information processing of sensory signals from afferent terminals to the spinal cord. SGCs use a variety ways to communicate with each other and with their enwrapped soma. Changes in this communication under injurious conditions often lead to abnormal pain conditions. "What are the mechanisms underlying the neuronal soma and SGC communication in sensory ganglia?" and "how do tissue or nerve injuries affect the communication?" are the main questions addressed in this review.
摘要
对感觉神经节中神经元（胞体）及其周围卫星胶质细胞（SGC）的结构组织和功能的研究，使人们认识到 SGC 积极参与从传入末梢到脊髓的感觉信号的信息处理。SGC 利用多种方式相互交流，并与它们包裹的胞体进行交流。在损伤条件下，这种通讯的变化常常导致异常的疼痛状况。“感觉神经节中神经元胞体和 SGC 通讯的机制是什么？”以及“组织或神经损伤如何影响通讯？”是本综述中主要探讨的问题。
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2
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3
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