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急性心力衰竭:患者特征与病理生理学

Acute heart failure: patient characteristics and pathophysiology.

作者信息

Marti Catherine N, Georgiopoulou Vasiliki V, Kalogeropoulos Andreas P

机构信息

Division of Cardiology, Emory University, Atlanta, GA, USA.

出版信息

Curr Heart Fail Rep. 2013 Dec;10(4):427-33. doi: 10.1007/s11897-013-0151-y.

DOI:10.1007/s11897-013-0151-y
PMID:23918642
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3823818/
Abstract

The number of hospitalizations for acute heart failure (HF) continues to increase and it remains the most common discharge diagnosis among Medicare beneficiaries. Prognosis after hospitalization for HF is poor, with high in-hospital mortality and even higher post-discharge mortality and rehospitalization rates. It is a complex clinical syndrome that varies widely with respect to clinical presentation and underlying pathophysiology. This paper reviews what is documented in the literature regarding the known pathophysiologic mechanisms reported in patients hospitalized for HF.

摘要

急性心力衰竭(HF)的住院人数持续增加,并且它仍然是医疗保险受益人中最常见的出院诊断。HF住院后的预后很差,住院死亡率高,出院后死亡率和再住院率甚至更高。它是一种复杂的临床综合征,临床表现和潜在病理生理学差异很大。本文回顾了文献中关于HF住院患者已知病理生理机制的记载。

相似文献

1
Acute heart failure: patient characteristics and pathophysiology.急性心力衰竭:患者特征与病理生理学
Curr Heart Fail Rep. 2013 Dec;10(4):427-33. doi: 10.1007/s11897-013-0151-y.
2
Acute heart failure: multiple clinical profiles and mechanisms require tailored therapy.急性心力衰竭:多种临床特征和机制需要针对性治疗。
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3
The Hospitalization Burden and Post-Hospitalization Mortality Risk in Heart Failure With Preserved Ejection Fraction: Results From the I-PRESERVE Trial (Irbesartan in Heart Failure and Preserved Ejection Fraction).射血分数保留的心力衰竭患者的住院负担和住院后死亡率风险:I-PRESERVE 试验(伊贝沙坦治疗心力衰竭和保留射血分数)的结果。
JACC Heart Fail. 2015 Jun;3(6):429-441. doi: 10.1016/j.jchf.2014.12.017. Epub 2015 May 14.
4
In-hospital and 1-year outcomes of acute heart failure patients according to presentation (de novo vs. worsening) and ejection fraction. Results from IN-HF Outcome Registry.根据临床表现(新发与恶化)和射血分数划分的急性心力衰竭患者的院内及1年预后。来自IN-HF结局登记研究的结果
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5
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Hospitalization for worsening chronic heart failure.因慢性心力衰竭恶化而住院。
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Association of the Hospital Readmissions Reduction Program With Mortality Among Medicare Beneficiaries Hospitalized for Heart Failure, Acute Myocardial Infarction, and Pneumonia.医院再入院率降低计划与医疗保险受益人因心力衰竭、急性心肌梗死和肺炎住院的死亡率之间的关联。
JAMA. 2018 Dec 25;320(24):2542-2552. doi: 10.1001/jama.2018.19232.

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Influenza infection and heart failure-vaccination may change heart failure prognosis?流感感染与心力衰竭——接种疫苗会改变心力衰竭的预后吗?
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本文引用的文献

1
Echocardiographic changes during treatment of acute decompensated heart failure: insights from the ESCAPE trial.超声心动图在急性失代偿性心力衰竭治疗中的变化:ESCAPE 试验的见解。
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Independent prognostic value of functional mitral regurgitation in patients with heart failure. A quantitative analysis of 1256 patients with ischaemic and non-ischaemic dilated cardiomyopathy.功能性二尖瓣反流对心力衰竭患者的独立预后价值。1256 例缺血性和非缺血性扩张型心肌病患者的定量分析。
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3
Increased 90-day mortality in patients with acute heart failure with elevated copeptin: secondary results from the Biomarkers in Acute Heart Failure (BACH) study.心钠肽升高的急性心力衰竭患者 90 天死亡率增加:急性心力衰竭生物标志物研究(BACH)的次要结果。
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4
Effect of nesiritide in patients with acute decompensated heart failure.奈西立肽治疗失代偿性心力衰竭的疗效。
N Engl J Med. 2011 Jul 7;365(1):32-43. doi: 10.1056/NEJMoa1100171.
5
The IL-33/ST2 pathway--A new therapeutic target in cardiovascular disease.IL-33/ST2 通路——心血管疾病的新治疗靶点。
Pharmacol Ther. 2011 Aug;131(2):179-86. doi: 10.1016/j.pharmthera.2011.02.005. Epub 2011 Feb 26.
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Clinical development of pharmacologic agents for acute heart failure syndromes: a proposal for a mechanistic translational phase.急性心力衰竭综合征药物治疗的临床研究进展:提出一种机制转化阶段的建议。
Am Heart J. 2011 Feb;161(2):224-32. doi: 10.1016/j.ahj.2010.10.023. Epub 2010 Dec 28.
7
β-trace protein and cystatin C as predictors of long-term outcomes in patients with acute heart failure.β-痕迹蛋白和胱抑素 C 可预测急性心力衰竭患者的长期预后。
J Am Coll Cardiol. 2011 Feb 15;57(7):849-58. doi: 10.1016/j.jacc.2010.08.644.
8
Clinical significance of matrix metalloproteinase (MMP)-2 in patients with acute heart failure.基质金属蛋白酶(MMP)-2在急性心力衰竭患者中的临床意义
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Kidney injury molecule-1.肾损伤分子-1。
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Emergence of blood urea nitrogen as a biomarker of neurohormonal activation in heart failure.血尿素氮作为心力衰竭神经激素激活的生物标志物的出现。
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