Michigan State University, USA.
Neurology. 2013 Aug 6;81(6):585-8. doi: 10.1212/WNL.0b013e31829e6ed5.
Radiologic data are increasingly important in clinical care guidelines for neurologic disorders and in the conduct of clinical trials assessing novel therapies. The infrastructure and expertise for neuroradiologic evaluations remain scarce in resource-limited settings, but where available, MRI and CT capacity can offer new insights into common, globally devastating diseases. In vivo data for frequently fatal tropical conditions such as cerebral malaria have been largely limited to autopsy studies, which only provide information on nonsurvivors at a single point in time. New imaging facilities in sub-Saharan African offer opportunities for expanded research on tropical neurologic disorders. However, data management challenges hamper the research utility of radiologic evaluations.
放射学数据在神经疾病的临床护理指南和评估新型治疗方法的临床试验中变得越来越重要。在资源有限的环境中,神经放射学评估的基础设施和专业知识仍然稀缺,但在有条件的地方,MRI 和 CT 能力可以为常见的、在全球范围内具有破坏性的疾病提供新的见解。在经常致命的热带疾病(如脑疟疾)的活体数据在很大程度上仅限于尸检研究,这些研究仅提供在一个时间点上的非幸存者信息。撒哈拉以南非洲的新成像设施为热带神经疾病的扩展研究提供了机会。然而,数据管理挑战阻碍了放射学评估的研究效用。