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神经交互:一种促进大脑疟疾神经影像学研究的方法。

NeuroInterp: a method for facilitating neuroimaging research on cerebral malaria.

机构信息

Michigan State University, USA.

出版信息

Neurology. 2013 Aug 6;81(6):585-8. doi: 10.1212/WNL.0b013e31829e6ed5.

DOI:10.1212/WNL.0b013e31829e6ed5
PMID:23918861
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3775682/
Abstract

Radiologic data are increasingly important in clinical care guidelines for neurologic disorders and in the conduct of clinical trials assessing novel therapies. The infrastructure and expertise for neuroradiologic evaluations remain scarce in resource-limited settings, but where available, MRI and CT capacity can offer new insights into common, globally devastating diseases. In vivo data for frequently fatal tropical conditions such as cerebral malaria have been largely limited to autopsy studies, which only provide information on nonsurvivors at a single point in time. New imaging facilities in sub-Saharan African offer opportunities for expanded research on tropical neurologic disorders. However, data management challenges hamper the research utility of radiologic evaluations.

摘要

放射学数据在神经疾病的临床护理指南和评估新型治疗方法的临床试验中变得越来越重要。在资源有限的环境中,神经放射学评估的基础设施和专业知识仍然稀缺,但在有条件的地方,MRI 和 CT 能力可以为常见的、在全球范围内具有破坏性的疾病提供新的见解。在经常致命的热带疾病(如脑疟疾)的活体数据在很大程度上仅限于尸检研究,这些研究仅提供在一个时间点上的非幸存者信息。撒哈拉以南非洲的新成像设施为热带神经疾病的扩展研究提供了机会。然而,数据管理挑战阻碍了放射学评估的研究效用。

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本文引用的文献

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Magnetic resonance imaging in Malawi: contributions to clinical care, medical education and biomedical research.马拉维的磁共振成像:对临床护理、医学教育和生物医学研究的贡献。
Malawi Med J. 2011 Jun;23(2):60-4. doi: 10.4314/mmj.v23i2.70753.
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AJNR Am J Neuroradiol. 2012 Oct;33(9):1740-6. doi: 10.3174/ajnr.A3035. Epub 2012 Apr 19.
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