Division of Pediatric Neurology, Department of Pediatrics, University of British Columbia, Canada.
Pediatrics. 2013 Sep;132(3):e771-4. doi: 10.1542/peds.2012-2876. Epub 2013 Aug 5.
We present a case of a boy who developed obsessive-compulsive disorder (OCD) shortly after an episode of acute disseminated encephalomyelitis (ADEM). To our knowledge, this is the first report of the development of OCD in a child who has had ADEM. This presentation is consistent with our understanding of OCD as a complex genetic disease involving the cerebral white matter tracts, and may indicate a potential pathway for the development of OCD in genetically vulnerable individuals or a shared trigger for the development of pediatric acute-onset neuropsychiatric syndrome and ADEM.
我们报告了一例男孩病例，他在急性播散性脑脊髓炎 (ADEM) 发作后不久出现强迫症 (OCD)。据我们所知，这是首例患有 ADEM 的儿童出现 OCD 的报道。这种表现与我们对 OCD 的理解一致，即 OCD 是一种复杂的遗传疾病，涉及大脑白质束，这可能表明 OCD 在遗传易感性个体中的发展存在潜在途径，或者是儿科急性发作神经精神综合征和 ADEM 发展的共同触发因素。
