Chemical and Biomolecular Engineering and ‡Computer Science, Johns Hopkins University , Baltimore, Maryland 21218, United States.
Nano Lett. 2013 Sep 11;13(9):4006-13. doi: 10.1021/nl400881w. Epub 2013 Aug 15.
Control over when and where nanostructures arise is essential for the self-assembly of dynamic or multicomponent devices. We design and construct a DNA origami seed for the control of DAE-E tile DNA nanotube assembly. Seeds greatly accelerate nanotube nucleation and growth because they serve as nanotube nucleation templates. Seeds also control nanotube circumference. Simulations predict nanotube growth rates and suggest a small nucleation barrier remains when nanotubes grow from seeds.
对纳米结构何时以及何地出现的控制对于动态或多组分器件的自组装至关重要。我们设计并构建了一个 DNA 折纸种子，以控制 DAE-E 瓦片 DNA 纳米管的组装。种子大大加速了纳米管的成核和生长，因为它们充当纳米管成核模板。种子还控制纳米管的周长。模拟预测了纳米管的生长速率，并表明当纳米管从种子生长时，仍然存在一个小的成核势垒。
