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喉平滑肌肉瘤与鳞状细胞癌的罕见关联:两例报告

A rare association of leiomyosarcoma with squamous cell carcinoma of the larynx: two cases.

作者信息

Kara E, Cetik M F, Tuncer U, Uguz A

机构信息

Department of Otolaryngology, Ministry of Health, Kozan State Hospital, Adana, Turkey.

出版信息

J Laryngol Otol. 2013 Aug;127(8):828-31. doi: 10.1017/S0022215113001618. Epub 2013 Aug 7.

DOI:10.1017/S0022215113001618
PMID:23919956
Abstract

OBJECTIVE

To discuss the histopathogenesis and treatment choices for synchronous tumours of the larynx.

CASE REPORTS

We present two cases of synchronous laryngeal leiomyosarcoma and squamous cell carcinoma. The first case was an early-stage tumour and the second an advanced-stage tumour of the larynx. Selection of adequate treatment for synchronous tumours is difficult because of different spreading rates and metastatic patterns. Treatment choices for both the primary tumour site and the neck should be related to the stage of the squamous component of the tumour.

CONCLUSION

In such cases, the tumour location, tumour stage and lymphatic metastases must be carefully evaluated in order to make the optimum treatment choice. Treatment evaluation of the neck should be related to the stage of the squamous component of these synchronous tumours. Partial laryngectomy techniques may be preferred if the extent of the disease permits.

摘要

目的

探讨喉同步肿瘤的组织病理学发病机制及治疗选择。

病例报告

我们呈现两例喉平滑肌肉瘤与鳞状细胞癌同步发生的病例。第一例为早期肿瘤,第二例为晚期喉肿瘤。由于不同的扩散速率和转移模式,为同步肿瘤选择适当的治疗方法颇具难度。原发肿瘤部位和颈部的治疗选择应与肿瘤鳞状成分的分期相关。

结论

在此类病例中,必须仔细评估肿瘤位置、肿瘤分期及淋巴转移情况,以做出最佳治疗选择。颈部的治疗评估应与这些同步肿瘤的鳞状成分分期相关。如果病情允许,部分喉切除术技术可能更为可取。

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