Weingart A, Gruber A D, Kershaw O, Kohn B
Klinik und Poliklinik für kleine Haustiere, Freie Universität Berlin, Fachbereich Veterinärmedizin, Deutschland.
Schweiz Arch Tierheilkd. 2013 Aug;155(8):463-9. doi: 10.1024/0036-7281/a000492.
Hypernatremia due to different pathophysiological mechanisms results in a rise in plasma osmolality. Dependent on its severity and on the speed of its development hyperosmolality can be life-threatening. This article describes 2 dogs and 1 cat with central nervous system disorders (adenoma of the pituitary gland, cerebral trauma). All patients developed normovolemic hypernatremia due to pituitary gland and hypothalamus dysfunction, respectively. Plasma sodium concentrations ranged from 163 to 185 mmol/l. Neurological examinations revealed lethargy, disturbances of consciousness, and ataxia, respectively. The dogs had to be euthanased due to the grave prognosis, the cat with cerebral trauma survived.
由于不同病理生理机制导致的高钠血症会引起血浆渗透压升高。根据其严重程度和发展速度，高渗状态可能危及生命。本文描述了2只患有中枢神经系统疾病（垂体腺瘤、脑外伤）的犬和1只猫。所有患者分别因垂体和下丘脑功能障碍而发生等容性高钠血症。血浆钠浓度范围为163至185 mmol/L。神经学检查分别显示嗜睡、意识障碍和共济失调。由于预后严重，犬不得不实施安乐死，而患有脑外伤的猫存活了下来。
