MOE-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Shanghai 200092, China.
Environ Pollut. 2013 Nov;182:184-9. doi: 10.1016/j.envpol.2013.07.023. Epub 2013 Aug 3.
We determined the levels of prenatal Hg exposure in Wujiang City, located in the southeast of Taihu Lake in China's Jiangsu Province, and analyze the relationship between prenatal exposure to Hg and neonatal anthropometry, including birth weight, body length, and head circumference. From June 2009 to July 2010, a total of 213 mother-infant pairs were enrolled. The geometric means of Hg levels in maternal hair, fetal hair, placentas, and cord blood were 496.76 μg/kg, 233.94 μg/kg, 3.58 μg/kg, and 1.54 μg/L, respectively. The Hg levels detected in our study were significantly lower than those reported by previous studies. In addition, no significant correlations were found between Hg levels in maternal hair, fetal hair, placenta, or cord blood and neonatal anthropometrics. Together, our findings may be important for understanding the effects of prenatal exposure to Hg on newborns' development and have implications concerning the recommended dose for Hg.
我们测定了位于中国江苏省太湖东南岸的吴江市孕妇体内的汞暴露水平,并分析了产前汞暴露与新生儿体格发育(包括出生体重、身长和头围)之间的关系。2009 年 6 月至 2010 年 7 月,共纳入了 213 对母婴。母亲头发、胎儿头发、胎盘和脐血中汞水平的几何均数分别为 496.76μg/kg、233.94μg/kg、3.58μg/kg 和 1.54μg/L。与以往研究相比,我们研究中检测到的汞水平明显较低。此外,母亲头发、胎儿头发、胎盘和脐血中的汞水平与新生儿体格发育之间均无显著相关性。综上,我们的研究结果可能有助于理解产前汞暴露对新生儿发育的影响,对汞的推荐剂量具有启示意义。