Di Gregorio C, Bertazzoni M G, Botticelli A R, Fano R A, Sannicola C
Istituto di anatomia e istologia patologica, Università di Modena.
Pathologica. 1990 Mar-Apr;82(1078):193-8.
A new case of Wells' syndrome is reported. Histologically the infiltrate of eosinophils extended to the deep dermis and the subcutaneous fat. The characteristic flame figures are seen in the dermis. Ultrastructurally eosinophils were numerous half of then degranulated. No injury to the vessel walls and collagen bundles were observed. The Authors emphasized that Wells' syndrome is a distinctive entity clinical, on likely autoimmune basis, with multiple triggering factors and peculiar histopathologic but not diagnostic picture.
报告了一例新的威尔斯综合征病例。组织学上，嗜酸性粒细胞浸润延伸至真皮深层和皮下脂肪。在真皮中可见特征性的火焰状图形。超微结构上，嗜酸性粒细胞数量众多，其中一半发生脱颗粒。未观察到血管壁和胶原束损伤。作者强调，威尔斯综合征是一种独特的临床实体，可能基于自身免疫，有多种触发因素，具有特殊的组织病理学表现但并非诊断性特征。
