Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Int J Behav Nutr Phys Act. 2013 Aug 8;10:94. doi: 10.1186/1479-5868-10-94.
Higher physical activity (PA) levels are known to be associated with lower risk of death. Less attention, however, has been paid to directly evaluate the effect of PA on the time by which a certain fraction of the population has died.
A population-based cohort of 29,362 men 45 to 79 years of age was followed from January 1998 to December 2010. A total of 4,570 men died. PA was assessed through a self-administrated questionnaire. Adjusted differences in the number of months by which 10% (10th percentile) of the cohort has died, according to levels of total PA (TPA) and different domains of PA were estimated using Laplace regression.
Overall, the 10th survival percentile was 9.6 years, that is, 90% of the cohort lived longer than 9.6 years. We found a strong evidence of non-linearity between TPA and the 10th survival percentile (P-value < 0.001). Compared to men with the lowest TPA (29 metabolic equivalents (MET)-hrs/day), men with a median TPA (41 MET-hrs/day) had 30 months longer survival (95% CI: 25-35). Below the median TPA, every increment of 4 MET-hrs/day, approximately a 30 minutes brisk pace daily walk, was associated with a longer survival of 11 months (95% CI: 8-15). Above the median TPA additional activity was not significantly associated with better survival.
We found that a physically active lifestyle is associated with a substantial improvement in survival time, up to 2.5 years over 13 years of follow-up.
较高的身体活动（PA）水平与较低的死亡风险相关。然而，人们对直接评估 PA 对特定人群死亡时间的影响关注较少。
对 1998 年 1 月至 2010 年 12 月期间的一个 29362 名 45 至 79 岁男性的基于人群的队列进行了随访。共有 4570 名男性死亡。通过自我管理问卷评估 PA。使用拉普拉斯回归估计根据总 PA（TPA）水平和不同 PA 领域的水平，队列中 10%（第 10 百分位数）的人死亡的月数差异。
总体而言，第 10 个生存百分位数为 9.6 年，即 90%的队列寿命超过 9.6 年。我们发现 TPA 与第 10 个生存百分位数之间存在很强的非线性关系（P 值<0.001）。与 TPA 最低的男性（29 代谢当量（MET）-hrs/天）相比，TPA 中位数（41 MET-hrs/天）的男性生存时间延长了 30 个月（95%CI：25-35）。在 TPA 中位数以下，每增加 4 MET-hrs/天，大约相当于每天快走 30 分钟，生存时间延长 11 个月（95%CI：8-15）。在 TPA 中位数以上，额外的活动与更好的生存无关。
我们发现，积极的生活方式与生存时间的显著改善相关，在 13 年的随访中，可延长 2.5 年。
