Graduate School of Sport Sciences, Waseda University, 2-579-15 Mikajima, Tokorozawa, Saitama, 359-1192, Japan,
Eur J Appl Physiol. 2013 Oct;113(10):2621-7. doi: 10.1007/s00421-013-2703-y. Epub 2013 Aug 8.
Yoga stretching can be done comfortably and easily by beginners and older adults to compensate for lack of exercise or poor health maintenance. The aim of this study was to determine the effect of yoga stretching on mucosal immune functions, primarily human β-defensin 2 (HBD-2) in saliva.
Fifteen healthy adults (age, 60.4 ± 8.0 years) participated in the study. Participants rested for 90 min on the first day and performed yoga for 90 min on the second day. Measurements were carried out before and after rest or yoga. Saliva samples were collected by chewing a sterile cotton at a frequency of 60 cycles per min. Salivary HBD-2 concentration was measured using an enzyme-linked immunosorbent assay.
HBD-2 concentration after yoga stretching (165.4 ± 127.1 pg/mL) was significantly higher than that before yoga stretching (84.1 ± 63.4 pg/mL; p < 0.01). HBD-2 expression rate after yoga stretching (232.8 ± 192.9 pg/min) was significantly higher than that before yoga stretching (110.7 ± 96.8 pg/min; p < 0.01). HBD-2 concentration (p < 0.05) and HBD-2 expression rate (p < 0.01) at post on the second day (yoga) was significantly higher than that on the first day (rest). POMS score of anger-hostility was lower after yoga than before.
Yoga stretching for 90 min can increase salivary HBD-2 expression in older adults. Therefore, yoga stretching might be useful for older adults and athletes to maintain their health.
瑜伽拉伸对于初学者和老年人来说，可以轻松舒适地进行，以弥补缺乏运动或健康维护不佳的问题。本研究旨在确定瑜伽拉伸对黏膜免疫功能的影响，主要是唾液中的人β防御素 2（HBD-2）。
15 名健康成年人（年龄 60.4±8.0 岁）参与了这项研究。参与者在第一天休息 90 分钟，在第二天进行 90 分钟的瑜伽。在休息或瑜伽前后进行测量。通过以每分钟 60 次的频率咀嚼无菌棉来采集唾液样本。使用酶联免疫吸附测定法测量唾液中 HBD-2 的浓度。
瑜伽拉伸后的 HBD-2 浓度（165.4±127.1pg/mL）明显高于瑜伽拉伸前的 HBD-2 浓度（84.1±63.4pg/mL；p<0.01）。瑜伽拉伸后的 HBD-2 表达率（232.8±192.9pg/min）明显高于瑜伽拉伸前的 HBD-2 表达率（110.7±96.8pg/min；p<0.01）。第二天（瑜伽）的 HBD-2 浓度（p<0.05）和 HBD-2 表达率（p<0.01）明显高于第一天（休息）。瑜伽后 POMS 量表的愤怒敌意评分较低。
90 分钟的瑜伽拉伸可以增加老年人唾液中的 HBD-2 表达。因此，瑜伽拉伸对于老年人和运动员保持健康可能是有用的。
