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针对新冠长期症状的正念冥想干预:生物行为基因表达与神经免疫功能

Mindfulness Meditation Interventions for Long COVID: Biobehavioral Gene Expression and Neuroimmune Functioning.

作者信息

Porter Nicole, Jason Leonard A

机构信息

Center for Community Research, DePaul University, Chicago, IL, USA.

出版信息

Neuropsychiatr Dis Treat. 2022 Nov 8;18:2599-2626. doi: 10.2147/NDT.S379653. eCollection 2022.

DOI:10.2147/NDT.S379653
PMID:36387947
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9653042/
Abstract

Some individuals infected with SARS CoV-2 have developed Post-Acute Sequelae of SARS CoV-2 infection (PASC) or what has been referred to as Long COVID. Efforts are underway to find effective treatment strategies for those with Long COVID. One possible approach involves alternative medical interventions, which have been widely used to treat and manage symptoms of a variety of medical problems including post-viral infections. Meditation has been found to reduce fatigue and unrefreshing sleep, and for those with post-viral infections, it has enhanced immunity, and reduced inflammatory-driven pathogenesis. Our article summarizes the literature on what is known about mindfulness meditation interventions, and reviews evidence on how it may apply to those with Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Evidence is reviewed suggesting effective and sustainable outcomes may be achieved for symptomatology and underlying pathology of post-viral fatigue (PASC and ME/CFS).

摘要

一些感染了严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的个体出现了新冠后遗症(PASC),即所谓的“长新冠”。目前正在努力寻找针对“长新冠”患者的有效治疗策略。一种可能的方法是采用替代医学干预措施,这些措施已被广泛用于治疗和管理包括病毒感染后在内的各种医疗问题的症状。冥想已被发现可以减轻疲劳和改善睡眠质量,对于病毒感染后的患者,它还可以增强免疫力,并减少炎症驱动的发病机制。我们的文章总结了关于正念冥想干预措施的已知文献,并回顾了其如何应用于“长新冠”患者和肌痛性脑脊髓炎/慢性疲劳综合征(ME/CFS)患者的证据。经审查的证据表明,对于病毒感染后疲劳(PASC和ME/CFS)的症状和潜在病理,可能会取得有效且可持续的治疗效果。

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Impact of Meditation-Based Lifestyle Practices on Mindfulness, Wellbeing, and Plasma Telomerase Levels: A Case-Control Study.基于冥想的生活方式实践对正念、幸福感和血浆端粒酶水平的影响:一项病例对照研究。
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Persistence of SARS CoV-2 S1 Protein in CD16+ Monocytes in Post-Acute Sequelae of COVID-19 (PASC) up to 15 Months Post-Infection.新冠病毒感染后 15 个月,COVID-19 后急性后遗症(PASC)中 CD16+ 单核细胞中 SARS-CoV-2 S1 蛋白持续存在。
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