Kachurovskaia O S, Andrzheiuk N I, Smirnova N A, Ivanova V B
Ter Arkh. 1990;62(4):96-100.
Sarcoidosis ran a favourable course in 166 out of 179 patients. The active phase of sarcoidosis was characterized by dysproteinemia, high content of histamine, STH and beta-lipoproteins together with a decrease of HPI and total protein. More remarkable shifts were observed in patients afflicted with sarcoidosis of the intrathoracic lymph nodes and of the lungs. In the phase of regression, there was a unidirectional change in the majority of the parameters, which correlated with the process liability to the reverse development. It may be recommended that the content of histamine, HPI and beta-lipoproteins should be measured along with other parameters to estimate the process activity in patients with respiratory sarcoidosis.
179例患者中，166例结节病病情呈良性发展。结节病活动期的特征为蛋白异常血症、组胺、生长激素及β-脂蛋白含量升高，同时组胺结合蛋白及总蛋白含量降低。胸腔内淋巴结及肺部结节病患者的变化更为显著。在消退期，大多数参数呈单向变化，这与病情易于逆向发展相关。建议在评估呼吸道结节病患者的病情活动度时，除其他参数外，还应检测组胺、组胺结合蛋白及β-脂蛋白的含量。
