血管造影诊断的特发性肺动脉高压的临床关联
Clinical correlates of angiographically diagnosed idiopathic pulmonary hypertension.
作者信息
Gray H H, Morgan J M, Kerr I H, Miller G A
机构信息
Department of Cardiology, Brompton Hospital, London.
出版信息
Thorax. 1990 Jun;45(6):442-6. doi: 10.1136/thx.45.6.442.
During 1970-87 43 patients with unexplained pulmonary hypertension (mean pulmonary arterial pressure greater than 25 mm Hg) were admitted to the Brompton Hospital and classified by angiographic criteria as having either symmetrical peripheral pulmonary artery pruning (thought to represent primary plexogenic pulmonary arteriopathy), n = 21, or asymmetrical pulmonary arterial occlusions (thought to represent chronic thromboembolic disease), n = 22. Patients with symmetrical pulmonary arteriopathy had significantly higher mean pulmonary arterial pressures (67 mm Hg) at the time of presentation than those with asymmetrical pulmonary arteriopathy (49 mm Hg). Clinical distinction between these two groups was impossible. Survival from the time of diagnosis was similarly poor in the two groups (26 weeks and 38 weeks) and did not correlate with any of the haemodynamic measurements. The difficulties in making distinctions between these conditions are discussed.
在1970年至1987年期间，43例不明原因肺动脉高压（平均肺动脉压大于25 mmHg）患者入住布朗普顿医院，并根据血管造影标准分类为具有对称性外周肺动脉截断（被认为代表原发性丛状肺血管病），n = 21例，或不对称性肺动脉闭塞（被认为代表慢性血栓栓塞性疾病），n = 22例。呈现时，对称性肺血管病患者的平均肺动脉压（67 mmHg）显著高于不对称性肺血管病患者（49 mmHg）。这两组之间无法进行临床区分。两组从诊断时起的生存率同样较差（分别为26周和38周），且与任何血流动力学测量值均无相关性。文中讨论了区分这些病症的困难。
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