Fishman A J, Moser K M, Fedullo P F
Chest. 1983 Dec;84(6):679-83. doi: 10.1378/chest.84.6.679.
A retrospective review of 15 patients with angiographically- or biopsy-documented primary pulmonary hypertension was performed to assess the value of pulmonary perfusion scanning in noninvasively differentiating these patients from those with potentially operable, chronic (large-vessel) thromboembolic pulmonary hypertension. None of the 15 patients with primary pulmonary hypertension demonstrated a segmental or larger perfusion defect whereas such defects have been uniformly present in previous reports of patients with large-vessel thromboembolic pulmonary hypertension. While perfusion scans in primary pulmonary hypertension may show certain abnormalities, the presence of segmental or larger perfusion defects should suggest the diagnosis of potentially correctable, large-vessel thromboembolic pulmonary hypertension rather than small-vessel, obliterative (primary, idiopathic) pulmonary hypertension.
对15例经血管造影或活检证实的原发性肺动脉高压患者进行了回顾性研究，以评估肺灌注扫描在无创鉴别这些患者与潜在可手术的慢性（大血管）血栓栓塞性肺动脉高压患者方面的价值。15例原发性肺动脉高压患者均未出现节段性或更大的灌注缺损，而在先前关于大血管血栓栓塞性肺动脉高压患者的报告中，此类缺损一直存在。虽然原发性肺动脉高压的灌注扫描可能显示某些异常，但节段性或更大的灌注缺损的存在应提示可能可纠正的大血管血栓栓塞性肺动脉高压的诊断，而非小血管闭塞性（原发性、特发性）肺动脉高压。
