Department of Analytical Chemistry, Arrhenius Laboratory, Stockholm University, SE-10691 Stockholm, Sweden.
J Chromatogr A. 2013 Sep 13;1307:119-25. doi: 10.1016/j.chroma.2013.07.087. Epub 2013 Jul 26.
A high performance liquid chromatography-tandem mass spectrometry method utilizing electrospray ionization in positive and negative mode has been developed for the separation and detection of benzothiazole and benzotriazole derivates. Ultra-sonication assisted solvent extraction of these compounds has also been developed and the overall method demonstrated on a selected clothing textile and an automobile tire sample. Matrix effects and extraction recoveries, as well as linearity and limits of detection have been evaluated. The calibration curves spanned over more than two orders of magnitude with coefficients of correlation R(2)>0.99 and the limits of detection and the limits of quantification were in the range 1.7-58pg injected and 18-140pg/g, respectively. The extraction recoveries ranged between 69% and 102% and the matrix effects between 75% and 101%. Benzothiazole and benzotriazole derivates were determined in the textile sample and benzothiazole derivatives determined in the tire sample with good analytical performance.
建立了一种利用电喷雾正、负离子模式的高效液相色谱-串联质谱法，用于苯并噻唑和苯并三唑衍生物的分离和检测。还开发了超声辅助溶剂萃取这些化合物的方法，并在选定的服装纺织品和汽车轮胎样品上进行了整体方法的演示。评估了基质效应和提取回收率，以及线性和检测限。校准曲线跨越了两个数量级以上，相关系数 R(2)>0.99，检测限和定量限的范围分别为 1.7-58pg 注入和 18-140pg/g。提取回收率在 69%至 102%之间，基质效应在 75%至 101%之间。对纺织品样品中的苯并噻唑和苯并三唑衍生物以及轮胎样品中的苯并噻唑衍生物进行了测定，分析性能良好。
