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[鼻分泌物的pH值和IgA测定——在职业医学中的可能用途——与功能相关的鼻科诊断]

[pH and IgA determination of nasal secretions--possible use in occupational medicine-rhinologic diagnosis in relation to function].

作者信息

Hummel K, Winkler U, Hennebach U

机构信息

Klinik für Hals-Nasen-Ohren-Krankheiten der Karl-Marx-Universität Leipzig.

出版信息

Z Gesamte Hyg. 1990 Jun;36(6):320-2.

PMID:2392849
Abstract

For the recognition of nasal lesions in exposure to non-toxic metallic dusts with crystalline SiO2-content in 100 foundry workers the in vitro determinations of the pH-value as well as the statement of IgA in the serum and nasal discharge were performed by means of simple radial immunodiffusion according to Mancini. The two functional-diagnostic method did not show any significant differences in comparison to the control groups. At present an use in the clinical and occupational-medical practice cannot be recommended.

摘要

为了识别100名铸造工人接触含100%结晶二氧化硅的无毒金属粉尘时的鼻部病变,采用根据曼奇尼法的简单放射免疫扩散法对pH值进行了体外测定,并对血清和鼻分泌物中的IgA进行了检测。与对照组相比,这两种功能诊断方法均未显示出任何显著差异。目前,不建议在临床和职业医学实践中使用。

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