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体力活动与心血管疾病风险:新的流行病学证据显示了什么?

Physical activity and risk of cardiovascular disease: what does the new epidemiological evidence show?

机构信息

Institute of Occupational and Social Medicine bInstitute of Medical Sociology, Center for Health and Society, Faculty of Medicine, University of Düsseldorf, Düsseldorf, Germany.

出版信息

Curr Opin Cardiol. 2013 Sep;28(5):575-83. doi: 10.1097/HCO.0b013e328364289c.

Abstract

PURPOSE OF REVIEW

Abundant evidence has documented inverse associations of physical activity and the risk of cardiovascular disease (CVD). However, the effects of different types of physical activity (e.g., leisure time and occupational physical activity) are still poorly understood.

RECENT FINDINGS

Drawing on recommended and established guidelines for study selection, we identified and included 23 prospective epidemiological studies published during the last 2 years. These studies included a total of more than 790 000 adults at baseline with some 22 000 incident cases occurring during follow-up. Our findings suggest that moderate and high levels of leisure time physical activity are associated with a moderately reduced risk of CVD. In contrast, moderate and high levels of occupational physical activity showed weak positive associations, that is, a slightly increased risk of CVD.

SUMMARY

This updated meta-analysis supports the notion of primary prevention of CVD through engagement in leisure time physical activity. The role of occupational physical activity in CVD prevention is questionable.

摘要

目的综述

大量证据表明,身体活动与心血管疾病(CVD)风险呈负相关。然而,不同类型的身体活动(如休闲时间和职业身体活动)的影响仍知之甚少。

最近的发现

根据研究选择的推荐和既定准则,我们确定并纳入了过去 2 年发表的 23 项前瞻性流行病学研究。这些研究共纳入了 79 万多名基线期成年人,随访期间发生了大约 22000 例新发病例。我们的研究结果表明,中等和高水平的休闲时间身体活动与 CVD 风险适度降低相关。相比之下,中等和高水平的职业身体活动表现出微弱的正相关,即 CVD 风险略有增加。

总结

本项更新的荟萃分析支持通过参与休闲时间身体活动来进行 CVD 的一级预防的观点。职业身体活动在 CVD 预防中的作用仍值得商榷。

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