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2013 年 1 月至 5 月法国爆发 NDM-1 产鲍曼不动杆菌。

Outbreak of NDM-1-producing Acinetobacter baumannii in France, January to May 2013.

机构信息

Department of Virology, Bacteriology - Infection Control, Parasitology -Mycology, Assistance Publique - Hôpitaux de Paris, University Hospital Henri Mondor, Créteil, France.

出版信息

Euro Surveill. 2013 Aug 1;18(31):20547. doi: 10.2807/1560-7917.es2013.18.31.20547.

Abstract

We report the first outbreak of carbapenem-resistant NDM-1-producing Acinetobacter baumannii in Europe, in a French intensive-care unit in January to May 2013. The index patient was transferred from Algeria and led to the infection/colonisation of five additional patients. Concurrently, another imported case from Algeria was identified. The seven isolates were genetically indistinguishable, belonging to ST85. The bla(NDM-1) carbapenemase gene was part of the chromosomally located composite transposon Tn125. This report underscores the growing concern about the spread of NDM-1-producing A. baumannii in Europe.

摘要

我们报告了欧洲首例碳青霉烯类耐药 NDM-1 型鲍曼不动杆菌的爆发,该起疫情发生于 2013 年 1 月至 5 月法国的一家重症监护病房。最初的感染源患者从阿尔及利亚转入该院,导致另外 5 名患者受到感染/定植。同时,还发现了另一起来自阿尔及利亚的输入性病例。7 株分离菌在基因上无法区分,均属于 ST85 型。bla(NDM-1)碳青霉烯酶基因位于染色体定位的复合转座子 Tn125 上。该报告突显了人们对欧洲 NDM-1 型鲍曼不动杆菌传播的日益关注。

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