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西班牙发生产OXA-23碳青霉烯酶的多重耐药鲍曼不动杆菌医院感染暴发。

Nosocomial outbreak of a multiresistant Acinetobacter baumannii expressing OXA-23 carbapenemase in Spain.

作者信息

Merino María, Poza Margarita, Roca Ignasi, Barba María José, Sousa Maria Dolores, Vila Jordi, Bou Germán

机构信息

1 Microbiology Department, Biomedical Research Institute-INIBIC, University Hospital A Coruña , A Coruña, Spain .

出版信息

Microb Drug Resist. 2014 Aug;20(4):259-63. doi: 10.1089/mdr.2013.0127. Epub 2013 Dec 11.

DOI:10.1089/mdr.2013.0127
PMID:24328852
Abstract

Carbapenem-resistant Acinetobacter baumannii isolates were obtained from 50 patients between July 2011 and July 2012 at the University Hospital A Coruña (NW Spain). These multidrug-resistant isolates, which belonged to a single clone, remained only susceptible to tigecycline, minocycline, and colistin and produced the carbapenem-hydrolyzing oxacillinase, OXA-23. This is the first reported outbreak of OXA-23-producing A. baumannii isolates in Spain.

摘要

2011年7月至2012年7月期间,在西班牙西北部拉科鲁尼亚大学医院,从50名患者身上分离出了耐碳青霉烯鲍曼不动杆菌菌株。这些多重耐药菌株属于单一克隆,仅对替加环素、米诺环素和黏菌素敏感,并产生碳青霉烯水解型苯唑西林酶OXA-23。这是西班牙首次报道的产OXA-23鲍曼不动杆菌菌株暴发。

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