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双胞胎处女膜异常——文献综述及病例报告

Hymenal anomalies in twins--review of the literature and case report.

作者信息

Watrowski Rafal, Jäger Christoph, Gerber Monika, Klein Catherina

机构信息

Division of Gynecology and Obstetrics, St. Josefskrankenhaus, Academic Teaching Hospital of the University of Freiburg, Sautierstr.1, 79104, Freiburg, Germany,

出版信息

Eur J Pediatr. 2014 Nov;173(11):1407-12. doi: 10.1007/s00431-013-2123-3. Epub 2013 Aug 11.

Abstract

UNLABELLED

Subocclusive hymenal variants, such as microperforate or septate hymen, impair somatic functions (e.g., vaginal intercourse or menstrual hygiene) and can negatively impact the quality of life of young women. We know little about the prevalence and inheritance of subocclusive hymenal variants. So far, eight cases of familial occurrence of occlusive hymenal anomalies (imperforate hymen) have been reported. In one of these cases, monozygotic twins were affected. We are reporting the first case of subocclusive hymenal variants (microperforate hymen and septate hymen) in 16-year-old white dizygotic twins. In addition, we review and discuss the current evidence.

CONCLUSION

The mode of inheritance of hymenal variants has not been determined so far. Because surgical corrections of hymenal variants should be carried out in asymptomatic patients (before menarche), gynecologists and pediatricians should keep in mind that familial occurrences may occur.

摘要

未标注

亚闭塞性处女膜变异,如微孔处女膜或纵隔处女膜,会损害躯体功能(如阴道性交或经期卫生),并可能对年轻女性的生活质量产生负面影响。我们对亚闭塞性处女膜变异的患病率和遗传情况知之甚少。到目前为止,已报告了8例闭塞性处女膜异常(处女膜闭锁)的家族性病例。其中1例为单卵双胞胎患病。我们报告了首例16岁白人双卵双胞胎患亚闭塞性处女膜变异(微孔处女膜和纵隔处女膜)的病例。此外,我们回顾并讨论了现有证据。

结论

处女膜变异的遗传方式迄今尚未确定。由于处女膜变异的手术矫正应在无症状患者(月经初潮前)中进行,妇科医生和儿科医生应牢记可能会出现家族性病例。

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