Department of Gynecology and Obstetrics, Military Instruction Hospital Mohammed V, Rabat, Morocco.
Faculty of Medicine and Pharmacy of Rabat, Mohammed V university, Rabat, Morocco.
Pan Afr Med J. 2022 Jul 15;42:207. doi: 10.11604/pamj.2022.42.207.33418. eCollection 2022.
The imperforate hymen and transverse vaginal septum are female reproductive tract abnormalities. Their concurrent occurrence is rare. So far, no manifestation of both anomalies within the same family has been reported in the literature. We report the first familial case of two sisters having both mentioned abnormalities. Our patient was the youngest sister of a 14-year-old, who presented with cyclic lower abdominal pain. Clinical and imaging examinations showed an imperforate hymen with hematometrocolpos. In addition, the surgery confirmed a low transverse vaginal septum, which was resected using a virginity-preserving procedure. In conclusion, the presence of both mentioned abnormalities between siblings reflects a potential genetic etiology, also in order to avoid late diagnostics of such anomalies, the imperforate hymen must be screened in the birth room.
处女膜闭锁和阴道横隔是女性生殖道的畸形。它们同时发生的情况很少见。迄今为止，文献中尚无同一家庭中同时存在这两种异常的报道。我们报告了首例姐妹俩同时存在这两种异常的家族性病例。我们的患者是一名 14 岁少女的妹妹，她周期性地出现下腹痛。临床和影像学检查显示处女膜闭锁伴阴道积血。此外，手术证实存在低横隔阴道，采用保留处女膜的方法进行了切除。总之，兄弟姐妹之间同时存在这两种异常提示可能存在潜在的遗传病因，为了避免这些异常的延迟诊断，处女膜闭锁必须在产房进行筛查。
