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开普敦症状性儿童中 A 组链球菌 emm 型流行率和潜在疫苗覆盖率。

Group A streptococcal emm type prevalence among symptomatic children in Cape Town and potential vaccine coverage.

机构信息

From the *Department of Medicine, Groote Schuur Hospital and University of Cape Town; †Department of Clinical Laboratory Sciences, Division of Microbiology, National Health Service and University of Cape Town, Cape Town, South Africa; and ‡University of Tennessee Health Science Center, Memphis, TN.

出版信息

Pediatr Infect Dis J. 2014 Feb;33(2):208-10. doi: 10.1097/INF.0b013e3182a5c32a.

DOI:10.1097/INF.0b013e3182a5c32a
PMID:23934204
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3947201/
Abstract

The molecular epidemiology of group A streptococcal pharyngeal infections in children in the Vanguard Community of Cape Town revealed 26 emm types among 157 isolates from 742 subjects. Coverage of a 30-valent vaccine is predicted to be 95% of pharyngitis cases in this population at high risk of rheumatic fever.

摘要

在开普敦先锋社区儿童 A 组链球菌咽峡炎感染的分子流行病学研究中，从 742 名研究对象的 157 株分离株中发现了 26 种 emm 型。在该高危风湿热人群中，预计 30 价疫苗对咽峡炎病例的覆盖率为 95%。

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