From the First Department of Pediatrics, University of Athens, "Aghia Sophia" Children's Hospital, Athens, Greece.
Pediatr Infect Dis J. 2013 Nov;32(11):1284-5. doi: 10.1097/INF.0b013e3182a5c42b.
We describe 3 children who developed teeth and tongue discoloration while receiving intravenous linezolid for 2 to 3 weeks. Linezolid was coadministered with piperacillin-tazobactam or meropenem. Teeth and tongue discoloration was reversible with dental cleaning after discontinuation of linezolid. We review the published pediatric and adult cases regarding teeth and tongue discoloration after linezolid administration.
我们描述了 3 名儿童，他们在接受静脉注射利奈唑胺治疗 2 至 3 周时出现牙齿和舌头变色。利奈唑胺与哌拉西林他唑巴坦或美罗培南联合使用。停药后进行牙齿清洁可使牙齿和舌头变色可逆。我们回顾了已发表的关于利奈唑胺给药后儿童和成人牙齿和舌头变色的病例。
