Karaca Emine Esra, Özdek Şengül, Yalçin Nuriye Gökçen, Ekici Feyzahan
1 Department of Ophthalmology, Gazi University Medical Faculty, Ankara - Turkey.
Eur J Ophthalmol. 2014 Mar-Apr;24(2):202-8. doi: 10.5301/ejo.5000351. Epub 2013 Aug 9.
To assess intraobserver and interobserver reproducibility of the measurement of choroidal thickness by using enhanced depth imaging optical coherence tomography (EDI-OCT).
A prospective, cross-sectional study was performed at Gazi University Ophthalmology Department. The macular areas of the right eyes of 110 healthy volunteers with no ophthalmic or systemic disease were recruited. Choroidal thickness was measured at the fovea and at 1000-µm intervals from the foveal center in both temporal and nasal directions. Each examiner measured choroidal thickness 30 days after the first measurement to assess intraobserver variability. Interobserver and intraobserver reproducibility were described by intraclass correlation coefficient (ICC) and coefficient of variation (CV).
The mean age was 44.0 ± 14.7 years (range 18-70 years). The mean choroidal thickness at the fovea was 315.5 ± 78.6. All the parameters evaluated were highly reproducible. Intraobserver CV of choroidal thickness measurements ranged from 24.76% to 35.74%, and the CV of subfoveal choroidal thickness was 24.92. The intraobserver and interobserver intraclass correlation coefficient was greater than 0.90 for all the parameters. Repeatability was slightly better at locations not exceeding 400 µm.
Choroidal thickness measurements obtained by EDI-OCT showed good repeatability for healthy Turkish subjects; EDI-OCT examinations of choroid are reliable in healthy eyes.
通过增强深度成像光学相干断层扫描（EDI-OCT）评估脉络膜厚度测量的观察者内和观察者间的可重复性。
在加齐大学眼科进行了一项前瞻性横断面研究。招募了110名无眼科或全身性疾病的健康志愿者的右眼黄斑区。在黄斑中心凹以及在颞侧和鼻侧方向距黄斑中心凹1000μm间隔处测量脉络膜厚度。每位检查者在首次测量后30天测量脉络膜厚度，以评估观察者内变异性。观察者间和观察者内的可重复性通过组内相关系数（ICC）和变异系数（CV）来描述。
平均年龄为44.0±14.7岁（范围18 - 70岁）。黄斑中心凹处的平均脉络膜厚度为315.5±78.6。所有评估参数均具有高度可重复性。脉络膜厚度测量的观察者内CV范围为24.76%至35.74%，黄斑中心凹下脉络膜厚度的CV为24.92。所有参数的观察者内和观察者间组内相关系数均大于0.90。在不超过400μm的位置，重复性略好。
通过EDI-OCT获得的脉络膜厚度测量结果对健康的土耳其受试者显示出良好的可重复性；脉络膜的EDI-OCT检查在健康眼中是可靠的。
