使用两种不同方法测量脉络膜厚度时观察者间和观察者内的可重复性与再现性。
Inter- and intraobserver repeatability and reproducibility of choroidal thickness measurements using two different methods.
作者信息
Malamas Angelakis, Dervenis Nikolaos, Kilintzis Vasileios, Chranioti Angeliki, Topouzis Fotis
机构信息
Department of Ophthalmology, Aristotle University of Thessaloniki, AHEPA Hospital, St. Kiriakidi 1, 54621, Thessaloniki, Greece.
出版信息
Int Ophthalmol. 2019 May;39(5):1061-1069. doi: 10.1007/s10792-018-0909-z. Epub 2018 Mar 31.
PURPOSE
To measure the inter- and intraobserver repeatability and reproducibility of choroidal thickness measurements taken by the enhanced depth imaging of spectral-domain optical coherence tomography (EDI-OCT) in randomly selected subjects using two different protocols.
METHODS
Twenty subjects of the Thessaloniki Eye Study database were randomly selected. The participants underwent EDI-OCT, and the choroidal thickness was measured on EDI images using two different protocols. All images were assessed by two examiners independently in two sessions in different days.
RESULTS
The interobserver intraclass correlation coefficient (ICC) for average choroidal thickness was 0.944. The average ICC for central, Cmin, and Cmax choroidal thickness was 0.899, 0.863, and 0.955, respectively. The interobserver ICC for average choroidal volume was 0.932. Intraobserver repeatability ICC for grader 1 ranged between 0.925 and 0.9720 and for grader 2 between 0.913 and 0.994.
CONCLUSION
Choroidal thickness measurements by EDI-OCT showed a high inter- and intraobserver reproducibility.
目的
使用两种不同方案，测量在随机选择的受试者中，通过光谱域光学相干断层扫描增强深度成像（EDI-OCT）进行脉络膜厚度测量时观察者间和观察者内的重复性与再现性。
方法
从塞萨洛尼基眼研究数据库中随机选择20名受试者。参与者接受EDI-OCT检查，并使用两种不同方案在EDI图像上测量脉络膜厚度。所有图像由两名检查者在不同日期的两个时间段独立评估。
结果
平均脉络膜厚度的观察者间组内相关系数（ICC）为0.944。中央、最小和最大脉络膜厚度的平均ICC分别为0.899、0.863和0.955。平均脉络膜体积的观察者间ICC为0.932。分级者1的观察者内重复性ICC在0.925至0.9720之间，分级者2的观察者内重复性ICC在0.913至0.994之间。
结论
EDI-OCT测量脉络膜厚度显示出较高的观察者间和观察者内再现性。
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