Tang Jun, Liu Sufu, Zhang Liangyun, Chen Weixiong, Shi Sisi, Yu Qingqing, Tang Chao, Wang Yuejian
Department of Otolaryngology - Head and Neck Surgery, The First People's Hospital of Foshan, Foshan, Guangdong 528000;
Exp Ther Med. 2013 Jul;6(1):167-171. doi: 10.3892/etm.2013.1072. Epub 2013 Apr 23.
The aim of this study was to evaluate the therapeutic value of pathological indicators to predict the efficacy of endoscopic sinus surgery (ESS) in patients with chronic rhinosinusitis (CRS) with nasal polyps. A total of 53 patients with CRS with nasal polyps, who had undergone endoscopic surgery at least one year before, were surveyed for their clinical symptoms. Surgical specimen biopsies were consulted and related pathological indicators were measured. The association between the main symptoms of CRS with nasal polyps following ESS and pathological indicators were statistically analyzed. The main symptoms of patients with CRS with nasal polyps following ESS were nasal congestion, thick nasal discharge, rhinorrhea or sneezing. Goblet cells are associated with the symptoms of sneezing and thick nasal discharge, pathological gland formation is associated with dizziness, and the degree of tissue edema is associated with post-nasal discharge (P<0.05). Pathological indicators aid the prediction of the efficacy of nasal ESS in patients with CRS with nasal polyps.
本研究旨在评估病理指标对预测慢性鼻-鼻窦炎(CRS)伴鼻息肉患者内镜鼻窦手术(ESS)疗效的治疗价值。对至少在一年前接受过内镜手术的53例CRS伴鼻息肉患者的临床症状进行了调查。查阅手术标本活检资料并测量相关病理指标。对ESS术后CRS伴鼻息肉患者的主要症状与病理指标之间的关联进行了统计学分析。ESS术后CRS伴鼻息肉患者的主要症状为鼻塞、浓稠鼻涕、流涕或打喷嚏。杯状细胞与打喷嚏和浓稠鼻涕症状相关,病理性腺体形成与头晕相关,组织水肿程度与鼻后滴漏相关(P<0.05)。病理指标有助于预测CRS伴鼻息肉患者鼻腔ESS的疗效。