Division of Respirology, Al-Adan Hospital, Ahmadi, Kuwait.
Can Respir J. 2013 Jul-Aug;20(4):253-5. doi: 10.1155/2013/242045.
Multiple myeloma, a disorder commonly encountered in elderly patients, represents a malignant proliferation of plasma cells that primarily affects bone marrow. Pleural effusion as the presenting manifestation of the disease is uncommon. The authors report a case of multiple myeloma with unusual features presenting at a relatively young age with massive spontaneous hemothorax and multiple thoracic masses completely obscuring rib shadow on plain chest imaging. The patient demonstrated a good response to melphalan chemotherapy without recurrence of effusion or the need for additional chemical or surgical pleural interventions.
多发性骨髓瘤是一种常见于老年患者的疾病,是浆细胞的恶性增殖,主要影响骨髓。以胸腔积液为首发表现的疾病并不常见。作者报告了一例多发性骨髓瘤的不典型病例,该患者相对年轻,表现为大量自发性血胸和多个胸壁肿块,在普通胸部影像学上完全遮蔽了肋骨阴影。该患者对马法兰化疗反应良好,没有胸腔积液复发,也不需要额外的化学或手术胸膜介入。