Dey Vivek, Thawani Manasi
Department of Dermatology, Venereology and Leprosy, People's College of Medical Sciences & Research Centre, Bhopal, MP, India.
Pediatr Dermatol. 2013 Sep-Oct;30(5):579-83. doi: 10.1111/pde.12208. Epub 2013 Aug 13.
Loose anagen hair syndrome (LAHS) is an uncommonly reported autosomal dominant hair disorder with incomplete penetrance that primarily affects children but is occasionally seen in adults. LAHS is characterized by the ability to easily and painlessly extract unsheathed anagen hairs from the scalp with gentle traction. The hair is sparse and does not grow long. Usually the hairs are not fragile and do not have areas of breakage. Initially it was considered a rare, sporadic condition found predominantly in young white girls with blonde hair. Because autosomal dominant inheritance has been reported, it was suspected that the condition might be equally common in boys but was probably underdiagnosed.
松散生长期毛发综合征(LAHS)是一种常染色体显性遗传性毛发疾病,发病率较低,外显率不完全,主要影响儿童,但偶尔也可见于成人。LAHS的特点是通过轻轻牵拉就能轻松无痛地从头皮上拔出未被鞘膜包裹的生长期毛发。头发稀疏,不长。通常毛发不脆弱,没有断裂区域。最初,它被认为是一种罕见的散发性疾病,主要见于年轻的金发白人女孩。由于有常染色体显性遗传的报道,人们怀疑这种疾病在男孩中可能同样常见,但可能未得到充分诊断。