Price V H, Gummer C L
Department of Dermatology, Kaiser Permanente Medical Center, San Francisco, California.
J Am Acad Dermatol. 1989 Feb;20(2 Pt 1):249-56. doi: 10.1016/s0190-9622(89)70030-x.
A distinctive new hair condition, the loose anagen syndrome, features anagen hairs that are loosely anchored and easily pulled from the scalp. The children studied had sparse hair that did not grow long and that pulled easily from the scalp. The majority of patients were blond girls, aged 2 to 5 years, but both sexes and those with dark hair can be affected. The hair was not fragile, and easily pulled hairs were misshapen anagen hairs without external root sheaths. Histologic examination of the hair showed abnormal premature keratinization of Huxley's and Henle's layers of the inner root sheath in some samples. Length and density of hair gradually increased with age, but anagen hairs remained loosely anchored in adulthood. This report describes findings in 22 children and five adults with the loose anagen syndrome.
一种独特的新型毛发疾病——生长期松动综合征，其特征是生长期毛发固定不牢，很容易从头皮上拔出。接受研究的儿童头发稀疏，长不长，且很容易从头皮上拔出。大多数患者为2至5岁的金发女孩，但男女均可患病，黑发者也可能受影响。毛发并不脆弱，容易拔出的毛发是没有外根鞘的生长期毛发畸形。对毛发的组织学检查显示，在一些样本中，内根鞘的赫胥黎层和亨勒层存在异常的过早角质化。头发的长度和密度随年龄增长逐渐增加，但成年后生长期毛发仍固定不牢。本报告描述了22名儿童和5名患有生长期松动综合征的成年人的研究结果。
