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迈向磁共振直线加速器的参考剂量学:电离室读数的磁场修正。

Towards reference dosimetry for the MR-linac: magnetic field correction of the ionization chamber reading.

机构信息

Department of Radiotherapy, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.

出版信息

Phys Med Biol. 2013 Sep 7;58(17):5945-57. doi: 10.1088/0031-9155/58/17/5945. Epub 2013 Aug 12.

DOI:10.1088/0031-9155/58/17/5945
PMID:23938362
Abstract

In the UMC Utrecht a prototype MR-linac has been installed. The system consists of a 6 MV Elekta (Crawley, UK) linear accelerator and a 1.5 T Philips (Best, The Netherlands) Achieva MRI system. This paper investigates the feasibility to correct the ionization chamber reading for the magnetic field within the dosimetry calibration method described by Almond et al (1999 Med. Phys. 26 1847-70). Firstly, the feasibility of using an ionization chamber in an MR-linac was assessed by investigating possible influences of the magnetic field on NE2571 Farmer-type ionization chamber characteristics: linearity, repeatability, orientation in the magnetic field; and AAPM TG51 correction factor for voltage polarity and ion recombination. We found that these AAPM correction factors for the NE2571 chamber were not influenced by the magnetic field. Secondly, the influence of the permanent 1.5 T magnetic field on the NE2571 chamber reading was quantified. The reading is influenced by the magnetic field; therefore, a correction factor has been added. For the standardized setup used in this paper, the NE2571 chamber reading increases by 4.9% (± 0.2%) due to the transverse 1.5 T magnetic field. Dosimetry measurements in an MR-linac are feasible, if a setup-specific magnetic field correction factor (P1.5 T) for the charge reading is introduced. For the setup investigated in this paper, the P1.5 T has a value of 0.953.

摘要

在乌得勒支大学医学中心安装了一台原型磁共振直线加速器。该系统由 Elekta(克劳利,英国)6MV 线性加速器和飞利浦 1.5T Achieva MRI 系统组成。本文研究了在 Almond 等人(1999 年 Med. Phys. 26 1847-70)描述的剂量学校准方法中,为磁场校正电离室读数的可行性。首先,通过研究磁场对 NE2571 型 Farmer 电离室特性的可能影响,评估了在磁共振直线加速器中使用电离室的可行性:线性度、重复性、磁场中的方向;以及 AAPM TG51 用于电压极性和离子复合的校正因子。我们发现,这些 AAPM 对 NE2571 室的校正因子不受磁场影响。其次,量化了 1.5T 恒定磁场对 NE2571 室读数的影响。由于磁场的影响,读数会发生变化;因此,添加了一个校正因子。对于本文使用的标准化设置,由于横向 1.5T 磁场,NE2571 室读数增加了 4.9%(±0.2%)。如果引入用于电荷读数的特定于设置的磁场校正因子(P1.5T),则在磁共振直线加速器中进行剂量学测量是可行的。对于本文研究的设置,P1.5T 的值为 0.953。

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