证据表明 SIVsmm 仍在继续向人类传播：在科特迪瓦农村鉴定出新的 HIV-2 谱系。
Evidence for continuing cross-species transmission of SIVsmm to humans: characterization of a new HIV-2 lineage in rural Côte d'Ivoire.
机构信息
aUMI 233, IRD and University of Montpellier 1, Montpellier, France bDepartment of Diagnostics, Teaching Hospital, University of Bouake, Côte d'Ivoire cProject group Epidemiology of Highly Pathogenic Microorganisms RKI, Berlin, Germany dDepartment of Microbiology and Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
出版信息
AIDS. 2013 Sep 24;27(15):2488-91. doi: 10.1097/01.aids.0000432443.22684.50.
Abstract
HIV types 1 and 2 (HIV-1 and HIV-2) are the result of multiple cross-species transmissions of their simian counterparts (SIVs) to humans. We studied whether new SIVs lineages have been transmitted to humans in rural Côte d'Ivoire and identified a novel HIV-2 variant (HIV-2-07IC-TNP03) not related to any of the previously defined HIV-2 groups. This finding shows that sooty mangabey viruses continue to be transmitted to humans, causing new zoonotic outbreaks.
摘要
HIV 类型 1 和 2（HIV-1 和 HIV-2）是其灵长类对应物（SIV）多次跨物种传播到人类的结果。我们研究了在科特迪瓦农村地区是否有新的 SIV 谱系传播给人类，并发现了一种新型 HIV-2 变体（HIV-2-07IC-TNP03），与之前定义的任何 HIV-2 组都没有关系。这一发现表明，黑长尾猴病毒仍在继续传播给人类，引发新的人畜共患病暴发。
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