喀麦隆存在疑似 HIV-1 组 P 的确认。
Confirmation of putative HIV-1 group P in Cameroon.
机构信息
Abbott Diagnostics, Dept. 09NG/Building AP20, 100 Abbott Park Rd., Abbott Park, IL 60064-6015, USA.
出版信息
J Virol. 2011 Feb;85(3):1403-7. doi: 10.1128/JVI.02005-10. Epub 2010 Nov 17.
Abstract
We report the second human immunodeficiency virus (HIV) belonging to the new HIV type 1 (HIV-1) group P lineage that is closely related to the simian immunodeficiency virus found in gorillas. This virus was identified in an HIV-seropositive male hospital patient in Cameroon, confirming that the group P virus is circulating in humans. Results from screening 1,736 HIV-seropositive specimens collected in Cameroon indicate that HIV-1 group P infections are rare, accounting for only 0.06% of HIV infections. Despite its rarity, group P shows evidence of adaptation to humans.
摘要
我们报告了第二种人类免疫缺陷病毒（HIV），属于新的 HIV-1 组 P 谱系，与在大猩猩中发现的猿猴免疫缺陷病毒密切相关。该病毒是在喀麦隆的一名 HIV 血清阳性男性住院患者中发现的，证实了组 P 病毒正在人群中传播。对喀麦隆采集的 1736 份 HIV 血清阳性样本进行筛查的结果表明，HIV-1 组 P 感染非常罕见，仅占 HIV 感染的 0.06%。尽管其罕见，但组 P 显示出适应人类的迹象。
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