原发性开角型青光眼的Orbscan地形图

Orbscan topography in primary open-angle glaucoma.

作者信息

Arranz-Marquez Esther, Bolivar Gema, Piñero David P, Konstas Anastasios G P, Mikropoulos Dimitrios G, Teus Miguel A

机构信息

*MD, PhD †PhD Rey Juan Carlos Hospital, Móstoles, Madrid, Spain (EA-M); Novovision, Madrid, Spain (EA-M, MAT); "Príncipe de Asturias" Universitary Hospital, Madrid, Spain (GB, MAT); Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain (DPP); Foundation for the Visual Quality (FUNCAVIS), Alicante, Spain (DPP); 1st University, Department of Ophthalmology, AHEPA Hospital, Thessaloniki, Greece (AGPK, DGM); and University of Alcalá, Madrid, Spain (MAT).

出版信息

Optom Vis Sci. 2013 Oct;90(10):1098-103. doi: 10.1097/OPX.0000000000000019.

DOI:10.1097/OPX.0000000000000019

PMID:23939294

Abstract

PURPOSE

To compare anterior and posterior corneal curvatures between eyes with primary open-angle glaucoma (POAG) and healthy eyes.

METHODS

This is a prospective, cross-sectional, observer-masked study. A total of 138 white subjects (one eye per patient) were consecutively recruited; 69 eyes had POAG (study group), and the other 69 comprised a group of healthy control eyes matched for age and central corneal pachymetry with the study ones. Exclusion criteria included any corneal or ocular inflammatory disease, previous ocular surgery, or treatment with carbonic anhydrase inhibitors. The same masked observer performed Goldmann applanation tonometry, ultrasound pachymetry, and Orbscan II topography in all cases. Central corneal thickness, intraocular pressure, and anterior and posterior topographic elevation maps were analyzed and compared between both groups.

RESULTS

Patients with POAG had greater forward shifting of the posterior corneal surface than that in healthy control eyes (p < 0.01). Significant differences in anterior corneal elevation between controls and POAG eyes were also found (p < 0.01).

CONCLUSIONS

Primary open-angle glaucoma eyes have a higher elevation of the posterior corneal surface than that in central corneal thickness-matched nonglaucomatous eyes.

摘要

目的

比较原发性开角型青光眼（POAG）患者与健康人眼睛的角膜前、后曲率。

方法

这是一项前瞻性、横断面、观察者盲法研究。连续招募了138名白人受试者（每位患者一只眼睛）；69只眼睛患有POAG（研究组），另外69只构成一组与研究组年龄和中央角膜厚度相匹配的健康对照眼睛。排除标准包括任何角膜或眼部炎症性疾病、既往眼部手术或使用碳酸酐酶抑制剂治疗。所有病例均由同一位盲法观察者进行Goldmann压平眼压测量、超声测厚和Orbscan II地形图检查。分析并比较两组的中央角膜厚度、眼压以及前、后地形高度图。