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从肯尼亚蝙蝠中分离出的新型病毒——菲基里尼弹状病毒的分离与分子特征

Isolation and molecular characterization of Fikirini rhabdovirus, a novel virus from a Kenyan bat.

机构信息

Centers for Disease Control and Prevention, Division of Vector-borne Diseases, Arbovirus Diseases Branch, Fort Collins, CO, USA.

Centers for Disease Control and Prevention, Division of High Consequence Pathogens and Pathology, Poxvirus and Rabies Branch, Atlanta, GA, USA.

出版信息

J Gen Virol. 2013 Nov;94(Pt 11):2393-2398. doi: 10.1099/vir.0.053983-0. Epub 2013 Aug 12.

Abstract

Zoonotic and vector-borne pathogens have comprised a significant component of emerging human infections in recent decades, and bats are increasingly recognized as reservoirs for many of these disease agents. To identify novel pathogens associated with bats, we screened tissues of bats collected in Kenya. Virus isolates were identified by next generation sequencing of viral nucleic acid preparations from the infected cell culture supernatant and characterized. Here we report the identification of Fikirini rhabdovirus, a novel rhabdovirus isolated from a bat, Hipposideros vittatus, captured along the Kenyan coast.

摘要

人畜共患病和媒介传播病原体是近几十年来新出现的人类感染的重要组成部分,蝙蝠越来越被认为是许多这些疾病病原体的宿主。为了鉴定与蝙蝠相关的新型病原体,我们对在肯尼亚收集的蝙蝠组织进行了筛查。通过对感染细胞培养上清液中的病毒核酸制备物进行下一代测序来鉴定病毒分离株,并对其进行了特征描述。在此,我们报告了从捕获于肯尼亚沿海的 Hipposideros vittatus 蝙蝠中分离出的新型弹状病毒 Fikirini rhabdovirus 的鉴定。

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