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半月板修复:形态与功能。

Restoration of the meniscus: form and function.

机构信息

Ian Hutchinson, Laboratory for Tissue Engineering Regeneration & Repair, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021. (

出版信息

Am J Sports Med. 2014 Apr;42(4):987-98. doi: 10.1177/0363546513498503. Epub 2013 Aug 12.

Abstract

Over the past 2 decades there has been a profound shift in our perception of the role of the meniscus in the knee joint. Orthopaedic opinion now favors salvaging and restoring the damaged meniscus where possible. Basic science is characterizing its form (anatomy) and functionality (biological and biomechanical) in an attempt to understand the effect of meniscal injury and repair on the knee joint as a whole. The meniscus is a complex tissue and has warranted extensive basic science, translational, and clinical research to identify techniques to augment healing and even replace the meniscus. The application of quantitative magnetic resonance image sequencing to the meniscus and articular cartilage of the affected compartment promises to add a quantifiable outcome measure to the body of clinical evidence that supports restoration of the meniscus. This article discusses the recent advances and outcomes in the pursuit of meniscal restoration with particular focus on the use of augmentation strategies in meniscal repair, meniscal imaging, and translational strategies.

摘要

在过去的 20 年中,我们对半月板在膝关节中的作用的认识发生了深刻的变化。现在,骨科医生更倾向于尽可能地保留和修复受损的半月板。基础科学正在描述其形态(解剖学)和功能(生物学和生物力学),试图了解半月板损伤和修复对整个膝关节的影响。半月板是一种复杂的组织,需要广泛的基础科学、转化和临床研究来确定增强愈合甚至替代半月板的技术。定量磁共振图像序列在受影响关节的半月板和软骨中的应用有望为支持半月板修复的临床证据体系增加一个可量化的结果测量。本文讨论了半月板修复的最新进展和结果,特别关注半月板修复中增强策略、半月板成像和转化策略的应用。

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