Digestive Endoscopy Unit, Università Cattolica del Sacro Cuore, Gemelli University Hospital, Rome, Italy.
J Pediatr Gastroenterol Nutr. 2013 Dec;57(6):794-7. doi: 10.1097/MPG.0b013e3182a803f7.
Peroral endoscopic myotomy (POEM) is a new endoscopic technique for the treatment of esophageal achalasia, with excellent results in adults. Three children with classic-type achalasia (mean age 9.6 years) underwent POEM in a single center. Mean basal lower esophageal sphincter pressure and Eckard score were 34.6 mmHg and 5.3, respectively. Mean length of myotomy was 10 cm. On average, POEM was completed in 60.6 minutes. No patients experienced postoperative complications or gastroesophageal reflux disease. In the 2 patients who completed a 12-month follow-up, complete symptoms relief was documented (Eckard score 0), as well as a significant drop of the basal lower esophageal sphincter pressure.
经口内镜下肌切开术（POEM）是一种治疗食管失弛缓症的新内镜技术，在成人中取得了极好的效果。在一家中心，3 名经典型贲门失弛缓症患儿（平均年龄 9.6 岁）接受了 POEM 治疗。平均基础食管下括约肌压力和 Eckard 评分分别为 34.6mmHg 和 5.3。平均肌切开长度为 10cm。平均而言，POEM 完成时间为 60.6 分钟。无患者发生术后并发症或胃食管反流病。在完成 12 个月随访的 2 名患者中，均记录到完全缓解症状（Eckard 评分 0），基础食管下括约肌压力也显著下降。
