Conley Adam, Cho Brian H, Tye Gary W, Reavey-Cantwell John, Coelho Daniel, Fuller Christine E, Rhodes Jennifer L
Departments of Neurosurgery, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298, USA.
Childs Nerv Syst. 2014 Mar;30(3):521-6. doi: 10.1007/s00381-013-2254-x. Epub 2013 Aug 13.
Giant cell reparative granulomas are rare bone tumors. Although benign, these tumors are locally destructive and can be highly vascular. They seldom occur in the cranial vault. We describe a multidisciplinary approach to a case of giant cell reparative granuloma of the cranium in a 3-year-old patient.
A 3-year-old girl female referred to the pediatric neurosurgery department for evaluation of a retro-auricular mass. She had a history of recurrent otitis media with two subsequent courses of antibiotics without resolution. CT imaging revealed an expansive lesion located in the right mastoid region. Open surgical biopsy revealed a hemorrhagic tumor consistent with a giant cell reparative granuloma. Angiography identified a hypervascular tumor blush that was supplied by the occipital artery. Preoperative transcatheter embolization was performed followed by a multidisciplinary surgical resection and reconstruction. Blood loss was minimal, and the patient recovered well after surgery.
Preoperative endovascular embolization and a multidisciplinary intraoperative approach with primary resection and cranial vault reconstruction is an effective approach to hypervascular giant cell reparative granulomas.
巨细胞修复性肉芽肿是一种罕见的骨肿瘤。尽管这些肿瘤是良性的,但具有局部破坏性,且血管丰富。它们很少发生于颅顶。我们描述了对一名3岁患者的颅骨巨细胞修复性肉芽肿病例采取的多学科治疗方法。
一名3岁女童因耳后肿物前来小儿神经外科就诊。她有复发性中耳炎病史,曾接受两个疗程的抗生素治疗但未痊愈。CT成像显示右侧乳突区有一膨胀性病变。开放手术活检显示为与巨细胞修复性肉芽肿相符的出血性肿瘤。血管造影显示有枕动脉供血的高血运肿瘤染色。术前进行了经导管栓塞,随后进行了多学科手术切除和重建。术中失血极少,患者术后恢复良好。
术前血管内栓塞以及采用一期切除和颅顶重建的多学科手术方法是治疗高血运巨细胞修复性肉芽肿的有效方法。