小儿鼻腔侵袭性巨细胞肉芽肿
Pediatric aggressive giant cell granuloma of nasal cavity.
作者信息
Seo Sung Tae, Kwon Ki Ryun, Rha Ki-Sang, Kim Seon-Hwan, Kim Yong Min
机构信息
Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University School of Medicine, Daejeon, South Korea; Research Institute for Medical Science, Chungnam National University School of Medicine, Daejeon, South Korea.
Department of Neurosurgery, Chungnam National University School of Medicine, Daejeon, South Korea.
出版信息
Int J Surg Case Rep. 2015;16:67-70. doi: 10.1016/j.ijscr.2015.09.011. Epub 2015 Sep 18.
INTRODUCTION
Giant cell granuloma (GCG) is a non-neoplastic osseous proliferative lesion of unknown etiology. Although a benign disease process, GCG can be locally destructive. It is extremely rare to have a pediatric case of GCG occurring in the nasal cavity with intracranial invasion.
PRESENTATION OF CASE
We report a case of an aggressive and recurrent giant cell granuloma with intracranial invasion in a 10 years old female patient which was completely excised with endoscopic craniofacial resection.
DISCUSSION
A literature review on pathogenesis, diagnosis and management is also performed.
CONCLUSION
The most common treatment for giant cell granuloma is surgery, ranging from simple curettage to resection. However, it must be completely excised in cases of aggressive and extensive lesion because of the high recurrence rate after incomplete removal.
引言
巨细胞肉芽肿（GCG）是一种病因不明的非肿瘤性骨增殖性病变。尽管是良性疾病过程，但GCG可能具有局部破坏性。小儿鼻腔内发生的GCG伴颅内侵犯极为罕见。
病例介绍
我们报告一例10岁女性患者发生的侵袭性复发性巨细胞肉芽肿伴颅内侵犯，通过内镜颅面切除术将其完全切除。
讨论
还对发病机制、诊断和治疗进行了文献综述。
结论
巨细胞肉芽肿最常见的治疗方法是手术，从简单刮除术到切除术不等。然而，对于侵袭性和广泛性病变，由于不完全切除后复发率高，必须将其完全切除。
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