直肠癌低位前切除术后吻合口漏:吻合器吻合与压迫吻合的比较。

Anastomotic leakage after low anterior resection for rectal cancer: comparison of stapled versus compression anastomosis.

机构信息

Department of Surgery, St John of God Hospital, Johannes von Gott Platz 1, 1020, Vienna, Austria.

出版信息

Langenbecks Arch Surg. 2013 Oct;398(7):957-64. doi: 10.1007/s00423-013-1103-4. Epub 2013 Aug 15.

Abstract

PURPOSE

Surgical technique and perioperative management in rectal cancer surgery have been substantially improved and standardized during the last decades. However, anastomotic leakage following low anterior resection still is a significant problem. Based on animal experimental data of improved healing of compression anastomosis, we hypothesized that a compression anastomotic device might improve healing rates of the highest-risk anastomoses.

METHODS

All low anterior resections for rectal cancer performed or directly supervised by the senior author between January 2004 and June 2012 were analyzed. Only patients with a stapled or compression anastomosis located within 6 cm from the anal verge were included. Until December 2008, circular staplers were employed, while since January 2009, a novel compression anastomotic device was used for rectal reconstruction exclusively.

RESULTS

Out of 197 patients operated for rectal cancer, a total of 96 (34 females, 35.4 %) fulfilled inclusion criteria. Fifty-eight (60.4 %) were reconstructed with circular staplers and 38 (39.6 %) using a compression anastomotic device. Significantly, more laparoscopic procedures were recorded in the compression anastomosis group, but distribution of gender, age, body mass index, American Society of Anaesthesiologists score, rate of preoperative radiotherapy, tumor staging, or stoma diversion rate were similar. Anastomotic leakage was observed in seven cases (7/58, 12.1 %) in the stapled and twice (2/38, 5.3 %) in the compression anastomosis group (p = 0.26).

CONCLUSIONS

In this series, rectal reconstruction following low anterior resection using a novel compression anastomotic device was safe and (at least) equally effective compared to traditional circular staplers concerning leak rate.

摘要

目的

在过去几十年中,直肠癌手术的外科技术和围手术期管理得到了实质性的改进和标准化。然而,低位前切除术的吻合口漏仍然是一个重大问题。基于改善吻合口压缩愈合的动物实验数据,我们假设一种压缩吻合装置可能会提高最高风险吻合口的愈合率。

方法

分析 2004 年 1 月至 2012 年 6 月期间由资深作者进行或直接监督的所有低位前切除术。仅纳入吻合口位于肛缘 6cm 以内且采用吻合器吻合或压缩吻合的患者。直到 2008 年 12 月,使用圆形吻合器,而自 2009 年 1 月起,专门使用一种新型的压缩吻合装置进行直肠重建。

结果

在 197 例接受直肠癌手术的患者中,共有 96 例(女性 34 例,35.4%)符合纳入标准。58 例(60.4%)采用圆形吻合器重建,38 例(39.6%)采用压缩吻合装置。显著的是,在使用压缩吻合的组中记录到更多的腹腔镜手术,但性别、年龄、体重指数、美国麻醉医师协会评分、术前放疗率、肿瘤分期或造口转流率的分布相似。吻合口漏发生在吻合器组的 7 例(7/58,12.1%)和压缩吻合组的 2 例(2/38,5.3%)(p=0.26)。

结论

在本系列中,与传统的圆形吻合器相比,使用新型压缩吻合装置进行低位前切除术的直肠重建在安全性和(至少)吻合口漏发生率方面是安全且有效的。

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